Purified Anti-Human CD18 Antibody[TS1/18.1.2.11], Functional Grade (E-AB-F10570)
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For research use only.
| Alternate Names | MAC, MFI, LFA, ITGB, Integrin beta, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, ITGB2, Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta, Complement receptor C3 subunit beta, Integrin beta-2, &, beta-2 integrin-n, 95 subunit beta, 959 beta subunit precursor), Beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit), CD 18, CD18/11B, CD18/11C, Cell surface adhesion glycoprotein LFA 1/CR3/P150, Cell surface adhesion glycoproteins LFA 1/CR3/p150, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement component 3 receptor 3 and 4 subunit, Complement receptor C3 beta subunit, Integrin, Integrin beta 2, Integrin beta chain beta 2, Integrin beta-2 (ITGB2), ITB2, Leukocyte associated antigens CD18/11A, Leukocyte cell adhesion molecule CD18, LFA 1, LFA1, Lymphocyte function associated antigen 1, Lymphocyte function associated antigen 1 (LFA1), MAC 1, MAC1, Macrophage antigen 1 (mac1) beta, OTTHUMP00000115278, OTTHUMP00000115279, OTTHUMP00000115280, OTTHUMP00000115281, OTTHUMP00000115282 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee |
| Background | CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD18 protein |
| Abbre | CD18 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM;Block
|
| Research Areas | Signal Transduction;Immunology;Stem Cells |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Weulersse M, et al. Immunity. 2020 Oct;53(4):824-839. |
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